Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial.
Identifieur interne : 000395 ( Main/Exploration ); précédent : 000394; suivant : 000396Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial.
Auteurs : Jacob M. Van Laar [Royaume-Uni] ; Dominique Farge [France] ; Jacob K. Sont [Pays-Bas] ; Kamran Naraghi [Royaume-Uni] ; Zora Marjanovic [France] ; Jérôme Larghero [France] ; Annemie J. Schuerwegh [Pays-Bas] ; Erik W A. Marijt [Pays-Bas] ; Madelon C. Vonk [Pays-Bas] ; Anton V. Schattenberg [Pays-Bas] ; Marco Matucci-Cerinic ; Alexandre E. Voskuyl [Pays-Bas] ; Arjan A. Van De Loosdrecht [Pays-Bas] ; Thomas Daikeler [Suisse] ; Ina Kötter [Allemagne] ; Marc Schmalzing [Allemagne] ; Thierry Martin [France] ; Bruno Lioure [France] ; Stefan M. Weiner [Allemagne] ; Alexander Kreuter [Allemagne] ; Christophe Deligny ; Jean-Marc Durand [France] ; Paul Emery [Royaume-Uni] ; Klaus P. Machold [Autriche] ; Francoise Sarrot-Reynauld [France] ; Klaus Warnatz [Allemagne] ; Daniel F P. Adoue ; Joël Constans [France] ; Hans-Peter Tony [Allemagne] ; Nicoletta Del Papa [Italie] ; Athanasios Fassas [Grèce] ; Andrea Himsel [Allemagne] ; David Launay [France] ; Andrea Lo Monaco [Italie] ; Pierre Philippe [France] ; Isabelle Quéré [France] ; Éric Rich [Canada] ; Rene Westhovens [Belgique] ; Bridget Griffiths [Royaume-Uni] ; Riccardo Saccardi [Italie] ; Frank H. Van Den Hoogen [Pays-Bas] ; Willem E. Fibbe [Pays-Bas] ; Gérard Socié [France] ; Alois Gratwohl [Suisse] ; Alan Tyndall [Suisse]Source :
- JAMA [ 1538-3598 ] ; 2014.
English descriptors
- KwdEn :
- Adult, Autografts, Cyclophosphamide (administration & dosage), Cyclophosphamide (adverse effects), Female, Hematopoietic Stem Cell Transplantation (adverse effects), Humans, Immunosuppressive Agents (administration & dosage), Immunosuppressive Agents (adverse effects), Male, Middle Aged, Scleroderma, Diffuse (drug therapy), Survival Analysis.
- MESH :
- chemical , administration & dosage : Cyclophosphamide, Immunosuppressive Agents.
- chemical , adverse effects : Cyclophosphamide, Immunosuppressive Agents.
- adverse effects : Hematopoietic Stem Cell Transplantation.
- drug therapy : Scleroderma, Diffuse.
- Adult, Autografts, Female, Humans, Male, Middle Aged, Survival Analysis.
Abstract
High-dose immunosuppressive therapy and autologous hematopoietic stem cell transplantation (HSCT) have shown efficacy in systemic sclerosis in phase 1 and small phase 2 trials.
DOI: 10.1001/jama.2014.6368
PubMed: 25058083
Affiliations:
- Allemagne, Autriche, Belgique, Canada, France, Grèce, Italie, Pays-Bas, Royaume-Uni, Suisse
- Alsace (région administrative), Angleterre, Aquitaine, Auvergne (région administrative), Auvergne-Rhône-Alpes, Bade-Wurtemberg, Bavière, District de Basse-Franconie, District de Darmstadt, District de Fribourg-en-Brisgau, District de Tübingen, Grand Est, Gueldre, Hauts-de-France, Hesse (Land), Hollande-Méridionale, Hollande-Septentrionale, Languedoc-Roussillon, Lombardie, Nord-Pas-de-Calais, Nouvelle-Aquitaine, Occitanie (région administrative), Provence-Alpes-Côte d'Azur, Rhône-Alpes, Vienne (Autriche), Yorkshire-et-Humber, Île-de-France
- Amsterdam, Bordeaux, Clermont-Ferrand, Francfort-sur-le-Main, Fribourg-en-Brisgau, Grenoble, Leeds, Leyde, Lille, Marseille, Milan, Montpellier, Nimègue, Paris, Strasbourg, Tübingen, Vienne (Autriche), Wurtzbourg
- Université de Leeds
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Le document en format XML
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Van Laar</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne</wicri:regionArea><wicri:noRegion>Newcastle upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Farge, Dominique" sort="Farge, Dominique" uniqKey="Farge D" first="Dominique" last="Farge">Dominique Farge</name><affiliation wicri:level="1"><nlm:affiliation>Internal Medicine and Vascular Disease Unit, AP-HP Hôpital Saint-Louis, Paris 7 University, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Internal Medicine and Vascular Disease Unit, AP-HP Hôpital Saint-Louis, Paris 7 University</wicri:regionArea><wicri:noRegion>Paris 7 University</wicri:noRegion><wicri:noRegion>Paris 7 University</wicri:noRegion></affiliation></author><author><name sortKey="Sont, Jacob K" sort="Sont, Jacob K" uniqKey="Sont J" first="Jacob K" last="Sont">Jacob K. Sont</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Decision Making, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Medical Decision Making, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Naraghi, Kamran" sort="Naraghi, Kamran" uniqKey="Naraghi K" first="Kamran" last="Naraghi">Kamran Naraghi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, The James Cook University Hospital, Middlesbrough, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Rheumatology, The James Cook University Hospital, Middlesbrough</wicri:regionArea><wicri:noRegion>Middlesbrough</wicri:noRegion></affiliation></author><author><name sortKey="Marjanovic, Zora" sort="Marjanovic, Zora" uniqKey="Marjanovic Z" first="Zora" last="Marjanovic">Zora Marjanovic</name><affiliation wicri:level="3"><nlm:affiliation>Service d'Hématologie Clinique et de Thérapie Cellulaire, AP-HP Hôpital Saint-Antoine, Paris 6 University, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service d'Hématologie Clinique et de Thérapie Cellulaire, AP-HP Hôpital Saint-Antoine, Paris 6 University, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Larghero, Jerome" sort="Larghero, Jerome" uniqKey="Larghero J" first="Jérôme" last="Larghero">Jérôme Larghero</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Investigation Center in Biotherapies and Cell Therapy Unit, AP-HP Hôpital Saint-Louis, Paris 7 University, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Clinical Investigation Center in Biotherapies and Cell Therapy Unit, AP-HP Hôpital Saint-Louis, Paris 7 University</wicri:regionArea><wicri:noRegion>Paris 7 University</wicri:noRegion><wicri:noRegion>Paris 7 University</wicri:noRegion></affiliation></author><author><name sortKey="Schuerwegh, Annemie J" sort="Schuerwegh, Annemie J" uniqKey="Schuerwegh A" first="Annemie J" last="Schuerwegh">Annemie J. Schuerwegh</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Rheumatology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Marijt, Erik W A" sort="Marijt, Erik W A" uniqKey="Marijt E" first="Erik W A" last="Marijt">Erik W A. Marijt</name><affiliation wicri:level="3"><nlm:affiliation>Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Hematology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Vonk, Madelon C" sort="Vonk, Madelon C" uniqKey="Vonk M" first="Madelon C" last="Vonk">Madelon C. Vonk</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Schattenberg, Anton V" sort="Schattenberg, Anton V" uniqKey="Schattenberg A" first="Anton V" last="Schattenberg">Anton V. Schattenberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Hematology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Hematology, Radboud University Nijmegen Medical Center, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Matucci Cerinic, Marco" sort="Matucci Cerinic, Marco" uniqKey="Matucci Cerinic M" first="Marco" last="Matucci-Cerinic">Marco Matucci-Cerinic</name><affiliation><nlm:affiliation>Department of Biomedicine, Division of Rheumatology AOUC and Department of Experimental and Clinical Medicine, University of Florence, Florence.</nlm:affiliation><wicri:noCountry code="subField">Florence</wicri:noCountry></affiliation></author><author><name sortKey="Voskuyl, Alexandre E" sort="Voskuyl, Alexandre E" uniqKey="Voskuyl A" first="Alexandre E" last="Voskuyl">Alexandre E. Voskuyl</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, VU University Medical Center, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Rheumatology, VU University Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Van De Loosdrecht, Arjan A" sort="Van De Loosdrecht, Arjan A" uniqKey="Van De Loosdrecht A" first="Arjan A" last="Van De Loosdrecht">Arjan A. Van De Loosdrecht</name><affiliation wicri:level="3"><nlm:affiliation>Department of Hematology, VU University Medical Center, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Hematology, VU University Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Daikeler, Thomas" sort="Daikeler, Thomas" uniqKey="Daikeler T" first="Thomas" last="Daikeler">Thomas Daikeler</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Rheumatology, University Hospital Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Kotter, Ina" sort="Kotter, Ina" uniqKey="Kotter I" first="Ina" last="Kötter">Ina Kötter</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine II, University Hospital, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine II, University Hospital, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Schmalzing, Marc" sort="Schmalzing, Marc" uniqKey="Schmalzing M" first="Marc" last="Schmalzing">Marc Schmalzing</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine II, University Hospital, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine II, University Hospital, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Martin, Thierry" sort="Martin, Thierry" uniqKey="Martin T" first="Thierry" last="Martin">Thierry Martin</name><affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Immunology, Strasbourg University Hospital, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Clinical Immunology, Strasbourg University Hospital, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Lioure, Bruno" sort="Lioure, Bruno" uniqKey="Lioure B" first="Bruno" last="Lioure">Bruno Lioure</name><affiliation wicri:level="3"><nlm:affiliation>Service d'Hématologie et d'Oncologie, Unité de Greffe de Cellules Souches Hématopoïétiques, Centre Hospitalier Universitaire Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service d'Hématologie et d'Oncologie, Unité de Greffe de Cellules Souches Hématopoïétiques, Centre Hospitalier Universitaire Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Weiner, Stefan M" sort="Weiner, Stefan M" uniqKey="Weiner S" first="Stefan M" last="Weiner">Stefan M. Weiner</name><affiliation wicri:level="1"><nlm:affiliation>2.Medizinische Abteilung Krankenhaus der Barmherzigen Brüder Trier, Trier, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>2.Medizinische Abteilung Krankenhaus der Barmherzigen Brüder Trier, Trier</wicri:regionArea><wicri:noRegion>Trier</wicri:noRegion><wicri:noRegion>Trier</wicri:noRegion><wicri:noRegion>Trier</wicri:noRegion></affiliation></author><author><name sortKey="Kreuter, Alexander" sort="Kreuter, Alexander" uniqKey="Kreuter A" first="Alexander" last="Kreuter">Alexander Kreuter</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Venereology, and Allergology, HELIOS St. Elisabeth Hospital Oberhausen, Oberhausen,Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology, and Allergology, HELIOS St. Elisabeth Hospital Oberhausen, Oberhausen</wicri:regionArea><wicri:noRegion>Oberhausen</wicri:noRegion><wicri:noRegion>Oberhausen</wicri:noRegion><wicri:noRegion>Oberhausen</wicri:noRegion></affiliation></author><author><name sortKey="Deligny, Christophe" sort="Deligny, Christophe" uniqKey="Deligny C" first="Christophe" last="Deligny">Christophe Deligny</name><affiliation><nlm:affiliation>Service Médecine Interne, Hôpital Pierre Zobda Quitman, Fort-de France, Martinique.</nlm:affiliation><wicri:noCountry code="subField">Martinique</wicri:noCountry></affiliation></author><author><name sortKey="Durand, Jean Marc" sort="Durand, Jean Marc" uniqKey="Durand J" first="Jean-Marc" last="Durand">Jean-Marc Durand</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine CHU La Conception, Assistance Publique-Hôpitaux de Marseille, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Internal Medicine CHU La Conception, Assistance Publique-Hôpitaux de Marseille, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Emery, Paul" sort="Emery, Paul" uniqKey="Emery P" first="Paul" last="Emery">Paul Emery</name><affiliation wicri:level="4"><nlm:affiliation>Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds</wicri:regionArea><orgName type="university">Université de Leeds</orgName><placeName><settlement type="city">Leeds</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Yorkshire-et-Humber</region></placeName></affiliation></author><author><name sortKey="Machold, Klaus P" sort="Machold, Klaus P" uniqKey="Machold K" first="Klaus P" last="Machold">Klaus P. Machold</name><affiliation wicri:level="3"><nlm:affiliation>Klinische Abteilung für Rheumatologie, Medizinische Universität, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Klinische Abteilung für Rheumatologie, Medizinische Universität, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Sarrot Reynauld, Francoise" sort="Sarrot Reynauld, Francoise" uniqKey="Sarrot Reynauld F" first="Francoise" last="Sarrot-Reynauld">Francoise Sarrot-Reynauld</name><affiliation wicri:level="3"><nlm:affiliation>Pôle Pluridisciplinaire de Médecine, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Pôle Pluridisciplinaire de Médecine, Centre Hospitalier Universitaire de Grenoble, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation></author><author><name sortKey="Warnatz, Klaus" sort="Warnatz, Klaus" uniqKey="Warnatz K" first="Klaus" last="Warnatz">Klaus Warnatz</name><affiliation wicri:level="3"><nlm:affiliation>Division of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Freiburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Freiburg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author><author><name sortKey="Adoue, Daniel F P" sort="Adoue, Daniel F P" uniqKey="Adoue D" first="Daniel F P" last="Adoue">Daniel F P. Adoue</name><affiliation><nlm:affiliation>Service Médecine Interne, Centre Hospitalier Universitaire Toulouse.</nlm:affiliation><wicri:noCountry code="subField">Centre Hospitalier Universitaire Toulouse</wicri:noCountry></affiliation></author><author><name sortKey="Constans, Joel" sort="Constans, Joel" uniqKey="Constans J" first="Joël" last="Constans">Joël Constans</name><affiliation wicri:level="3"><nlm:affiliation>Service Médecine Interne et Médecine Vasculaire, Hôpital St-André, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service Médecine Interne et Médecine Vasculaire, Hôpital St-André, Centre Hospitalier Universitaire de Bordeaux, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Tony, Hans Peter" sort="Tony, Hans Peter" uniqKey="Tony H" first="Hans-Peter" last="Tony">Hans-Peter Tony</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology and Clinical Immunology, University of Würzburg Medical Center, Würzburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Rheumatology and Clinical Immunology, University of Würzburg Medical Center, Würzburg</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Basse-Franconie</region><settlement type="city">Wurtzbourg</settlement></placeName></affiliation></author><author><name sortKey="Del Papa, Nicoletta" sort="Del Papa, Nicoletta" uniqKey="Del Papa N" first="Nicoletta" last="Del Papa">Nicoletta Del Papa</name><affiliation wicri:level="3"><nlm:affiliation>Day Hospital Reumatologia, Ospedale G. Pini, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Day Hospital Reumatologia, Ospedale G. Pini, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Fassas, Athanasios" sort="Fassas, Athanasios" uniqKey="Fassas A" first="Athanasios" last="Fassas">Athanasios Fassas</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hematology, Cell and Gene Therapy Center, George Papanicolaou Hospital, Thessaloniki, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Hematology, Cell and Gene Therapy Center, George Papanicolaou Hospital, Thessaloniki</wicri:regionArea><wicri:noRegion>Thessaloniki</wicri:noRegion></affiliation></author><author><name sortKey="Himsel, Andrea" sort="Himsel, Andrea" uniqKey="Himsel A" first="Andrea" last="Himsel">Andrea Himsel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, University Hospital Frankfurt, Frankfurt, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Rheumatology, University Hospital Frankfurt, Frankfurt</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Launay, David" sort="Launay, David" uniqKey="Launay D" first="David" last="Launay">David Launay</name><affiliation wicri:level="3"><nlm:affiliation>Service de Médecine Interne, Hôpital Claude-Huriez, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service de Médecine Interne, Hôpital Claude-Huriez, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Lo Monaco, Andrea" sort="Lo Monaco, Andrea" uniqKey="Lo Monaco A" first="Andrea" last="Lo Monaco">Andrea Lo Monaco</name><affiliation wicri:level="1"><nlm:affiliation>Section and Unit of Rheumatology, Department of Medical Sciences, University of Ferrara, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Section and Unit of Rheumatology, Department of Medical Sciences, University of Ferrara</wicri:regionArea><wicri:noRegion>University of Ferrara</wicri:noRegion></affiliation></author><author><name sortKey="Philippe, Pierre" sort="Philippe, Pierre" uniqKey="Philippe P" first="Pierre" last="Philippe">Pierre Philippe</name><affiliation wicri:level="3"><nlm:affiliation>Service de Médecine Interne, Centre Hospitalier Universitaire Estaing, Clermont-Ferrand, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service de Médecine Interne, Centre Hospitalier Universitaire Estaing, Clermont-Ferrand</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Auvergne (région administrative)</region><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author><author><name sortKey="Quere, Isabelle" sort="Quere, Isabelle" uniqKey="Quere I" first="Isabelle" last="Quéré">Isabelle Quéré</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine, Montpellier University Hospital, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Internal Medicine, Montpellier University Hospital, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Rich, Eric" sort="Rich, Eric" uniqKey="Rich E" first="Éric" last="Rich">Éric Rich</name><affiliation wicri:level="1"><nlm:affiliation>Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre Hospitalier de l'Université de Montréal, Montréal, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Westhovens, Rene" sort="Westhovens, Rene" uniqKey="Westhovens R" first="Rene" last="Westhovens">Rene Westhovens</name><affiliation wicri:level="1"><nlm:affiliation>Skeletal Biology and Engineering Research Center, Department of Development and Regeneration KU Leuven, Rheumatology, University Hospitals, Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Skeletal Biology and Engineering Research Center, Department of Development and Regeneration KU Leuven, Rheumatology, University Hospitals, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Griffiths, Bridget" sort="Griffiths, Bridget" uniqKey="Griffiths B" first="Bridget" last="Griffiths">Bridget Griffiths</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, Freeman Hospital, Newcastle upon Tyne, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Rheumatology, Freeman Hospital, Newcastle upon Tyne</wicri:regionArea><wicri:noRegion>Newcastle upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Saccardi, Riccardo" sort="Saccardi, Riccardo" uniqKey="Saccardi R" first="Riccardo" last="Saccardi">Riccardo Saccardi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hematology, Careggi University Hospital, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Hematology, Careggi University Hospital, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Van Den Hoogen, Frank H" sort="Van Den Hoogen, Frank H" uniqKey="Van Den Hoogen F" first="Frank H" last="Van Den Hoogen">Frank H. Van Den Hoogen</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, Maartenskliniek, Nijmegen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Rheumatology, Maartenskliniek, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Fibbe, Willem E" sort="Fibbe, Willem E" uniqKey="Fibbe W" first="Willem E" last="Fibbe">Willem E. Fibbe</name><affiliation wicri:level="3"><nlm:affiliation>Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Socie, Gerard" sort="Socie, Gerard" uniqKey="Socie G" first="Gérard" last="Socié">Gérard Socié</name><affiliation wicri:level="1"><nlm:affiliation>Hematology/Transplantation, AP-HP Hôpital Saint-Louis, Paris 7 University, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Hematology/Transplantation, AP-HP Hôpital Saint-Louis, Paris 7 University</wicri:regionArea><wicri:noRegion>Paris 7 University</wicri:noRegion><wicri:noRegion>Paris 7 University</wicri:noRegion></affiliation></author><author><name sortKey="Gratwohl, Alois" sort="Gratwohl, Alois" uniqKey="Gratwohl A" first="Alois" last="Gratwohl">Alois Gratwohl</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hematology, University Hospital Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Hematology, University Hospital Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Tyndall, Alan" sort="Tyndall, Alan" uniqKey="Tyndall A" first="Alan" last="Tyndall">Alan Tyndall</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Rheumatology, University Hospital Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:25058083</idno><idno type="pmid">25058083</idno><idno type="doi">10.1001/jama.2014.6368</idno><idno type="wicri:Area/PubMed/Corpus">000358</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000358</idno><idno type="wicri:Area/PubMed/Curation">000358</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000358</idno><idno type="wicri:Area/PubMed/Checkpoint">000358</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000358</idno><idno type="wicri:Area/Ncbi/Merge">000697</idno><idno type="wicri:Area/Ncbi/Curation">000697</idno><idno type="wicri:Area/Ncbi/Checkpoint">000697</idno><idno type="wicri:Area/Main/Merge">000396</idno><idno type="wicri:Area/Main/Curation">000395</idno><idno type="wicri:Area/Main/Exploration">000395</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Autologous hematopoietic stem cell transplantation vs intravenous pulse cyclophosphamide in diffuse cutaneous systemic sclerosis: a randomized clinical trial.</title><author><name sortKey="Van Laar, Jacob M" sort="Van Laar, Jacob M" uniqKey="Van Laar J" first="Jacob M" last="Van Laar">Jacob M. Van Laar</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne</wicri:regionArea><wicri:noRegion>Newcastle upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Farge, Dominique" sort="Farge, Dominique" uniqKey="Farge D" first="Dominique" last="Farge">Dominique Farge</name><affiliation wicri:level="1"><nlm:affiliation>Internal Medicine and Vascular Disease Unit, AP-HP Hôpital Saint-Louis, Paris 7 University, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Internal Medicine and Vascular Disease Unit, AP-HP Hôpital Saint-Louis, Paris 7 University</wicri:regionArea><wicri:noRegion>Paris 7 University</wicri:noRegion><wicri:noRegion>Paris 7 University</wicri:noRegion></affiliation></author><author><name sortKey="Sont, Jacob K" sort="Sont, Jacob K" uniqKey="Sont J" first="Jacob K" last="Sont">Jacob K. Sont</name><affiliation wicri:level="3"><nlm:affiliation>Department of Medical Decision Making, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Medical Decision Making, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Naraghi, Kamran" sort="Naraghi, Kamran" uniqKey="Naraghi K" first="Kamran" last="Naraghi">Kamran Naraghi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, The James Cook University Hospital, Middlesbrough, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Rheumatology, The James Cook University Hospital, Middlesbrough</wicri:regionArea><wicri:noRegion>Middlesbrough</wicri:noRegion></affiliation></author><author><name sortKey="Marjanovic, Zora" sort="Marjanovic, Zora" uniqKey="Marjanovic Z" first="Zora" last="Marjanovic">Zora Marjanovic</name><affiliation wicri:level="3"><nlm:affiliation>Service d'Hématologie Clinique et de Thérapie Cellulaire, AP-HP Hôpital Saint-Antoine, Paris 6 University, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service d'Hématologie Clinique et de Thérapie Cellulaire, AP-HP Hôpital Saint-Antoine, Paris 6 University, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Larghero, Jerome" sort="Larghero, Jerome" uniqKey="Larghero J" first="Jérôme" last="Larghero">Jérôme Larghero</name><affiliation wicri:level="1"><nlm:affiliation>Clinical Investigation Center in Biotherapies and Cell Therapy Unit, AP-HP Hôpital Saint-Louis, Paris 7 University, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Clinical Investigation Center in Biotherapies and Cell Therapy Unit, AP-HP Hôpital Saint-Louis, Paris 7 University</wicri:regionArea><wicri:noRegion>Paris 7 University</wicri:noRegion><wicri:noRegion>Paris 7 University</wicri:noRegion></affiliation></author><author><name sortKey="Schuerwegh, Annemie J" sort="Schuerwegh, Annemie J" uniqKey="Schuerwegh A" first="Annemie J" last="Schuerwegh">Annemie J. Schuerwegh</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Rheumatology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Marijt, Erik W A" sort="Marijt, Erik W A" uniqKey="Marijt E" first="Erik W A" last="Marijt">Erik W A. Marijt</name><affiliation wicri:level="3"><nlm:affiliation>Department of Hematology, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Hematology, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Vonk, Madelon C" sort="Vonk, Madelon C" uniqKey="Vonk M" first="Madelon C" last="Vonk">Madelon C. Vonk</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Rheumatology, Radboud University Nijmegen Medical Center, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Schattenberg, Anton V" sort="Schattenberg, Anton V" uniqKey="Schattenberg A" first="Anton V" last="Schattenberg">Anton V. Schattenberg</name><affiliation wicri:level="3"><nlm:affiliation>Department of Hematology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Hematology, Radboud University Nijmegen Medical Center, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Matucci Cerinic, Marco" sort="Matucci Cerinic, Marco" uniqKey="Matucci Cerinic M" first="Marco" last="Matucci-Cerinic">Marco Matucci-Cerinic</name><affiliation><nlm:affiliation>Department of Biomedicine, Division of Rheumatology AOUC and Department of Experimental and Clinical Medicine, University of Florence, Florence.</nlm:affiliation><wicri:noCountry code="subField">Florence</wicri:noCountry></affiliation></author><author><name sortKey="Voskuyl, Alexandre E" sort="Voskuyl, Alexandre E" uniqKey="Voskuyl A" first="Alexandre E" last="Voskuyl">Alexandre E. Voskuyl</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, VU University Medical Center, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Rheumatology, VU University Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Van De Loosdrecht, Arjan A" sort="Van De Loosdrecht, Arjan A" uniqKey="Van De Loosdrecht A" first="Arjan A" last="Van De Loosdrecht">Arjan A. Van De Loosdrecht</name><affiliation wicri:level="3"><nlm:affiliation>Department of Hematology, VU University Medical Center, Amsterdam, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Hematology, VU University Medical Center, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Daikeler, Thomas" sort="Daikeler, Thomas" uniqKey="Daikeler T" first="Thomas" last="Daikeler">Thomas Daikeler</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Rheumatology, University Hospital Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Kotter, Ina" sort="Kotter, Ina" uniqKey="Kotter I" first="Ina" last="Kötter">Ina Kötter</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine II, University Hospital, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine II, University Hospital, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Schmalzing, Marc" sort="Schmalzing, Marc" uniqKey="Schmalzing M" first="Marc" last="Schmalzing">Marc Schmalzing</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine II, University Hospital, Tübingen, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Internal Medicine II, University Hospital, Tübingen</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Tübingen</region><settlement type="city">Tübingen</settlement></placeName></affiliation></author><author><name sortKey="Martin, Thierry" sort="Martin, Thierry" uniqKey="Martin T" first="Thierry" last="Martin">Thierry Martin</name><affiliation wicri:level="3"><nlm:affiliation>Department of Clinical Immunology, Strasbourg University Hospital, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Clinical Immunology, Strasbourg University Hospital, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Lioure, Bruno" sort="Lioure, Bruno" uniqKey="Lioure B" first="Bruno" last="Lioure">Bruno Lioure</name><affiliation wicri:level="3"><nlm:affiliation>Service d'Hématologie et d'Oncologie, Unité de Greffe de Cellules Souches Hématopoïétiques, Centre Hospitalier Universitaire Hautepierre, Strasbourg, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service d'Hématologie et d'Oncologie, Unité de Greffe de Cellules Souches Hématopoïétiques, Centre Hospitalier Universitaire Hautepierre, Strasbourg</wicri:regionArea><placeName><region type="region">Grand Est</region><region type="old region">Alsace (région administrative)</region><settlement type="city">Strasbourg</settlement></placeName></affiliation></author><author><name sortKey="Weiner, Stefan M" sort="Weiner, Stefan M" uniqKey="Weiner S" first="Stefan M" last="Weiner">Stefan M. Weiner</name><affiliation wicri:level="1"><nlm:affiliation>2.Medizinische Abteilung Krankenhaus der Barmherzigen Brüder Trier, Trier, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>2.Medizinische Abteilung Krankenhaus der Barmherzigen Brüder Trier, Trier</wicri:regionArea><wicri:noRegion>Trier</wicri:noRegion><wicri:noRegion>Trier</wicri:noRegion><wicri:noRegion>Trier</wicri:noRegion></affiliation></author><author><name sortKey="Kreuter, Alexander" sort="Kreuter, Alexander" uniqKey="Kreuter A" first="Alexander" last="Kreuter">Alexander Kreuter</name><affiliation wicri:level="1"><nlm:affiliation>Department of Dermatology, Venereology, and Allergology, HELIOS St. Elisabeth Hospital Oberhausen, Oberhausen,Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Dermatology, Venereology, and Allergology, HELIOS St. Elisabeth Hospital Oberhausen, Oberhausen</wicri:regionArea><wicri:noRegion>Oberhausen</wicri:noRegion><wicri:noRegion>Oberhausen</wicri:noRegion><wicri:noRegion>Oberhausen</wicri:noRegion></affiliation></author><author><name sortKey="Deligny, Christophe" sort="Deligny, Christophe" uniqKey="Deligny C" first="Christophe" last="Deligny">Christophe Deligny</name><affiliation><nlm:affiliation>Service Médecine Interne, Hôpital Pierre Zobda Quitman, Fort-de France, Martinique.</nlm:affiliation><wicri:noCountry code="subField">Martinique</wicri:noCountry></affiliation></author><author><name sortKey="Durand, Jean Marc" sort="Durand, Jean Marc" uniqKey="Durand J" first="Jean-Marc" last="Durand">Jean-Marc Durand</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine CHU La Conception, Assistance Publique-Hôpitaux de Marseille, Marseille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Internal Medicine CHU La Conception, Assistance Publique-Hôpitaux de Marseille, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Emery, Paul" sort="Emery, Paul" uniqKey="Emery P" first="Paul" last="Emery">Paul Emery</name><affiliation wicri:level="4"><nlm:affiliation>Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds</wicri:regionArea><orgName type="university">Université de Leeds</orgName><placeName><settlement type="city">Leeds</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Yorkshire-et-Humber</region></placeName></affiliation></author><author><name sortKey="Machold, Klaus P" sort="Machold, Klaus P" uniqKey="Machold K" first="Klaus P" last="Machold">Klaus P. Machold</name><affiliation wicri:level="3"><nlm:affiliation>Klinische Abteilung für Rheumatologie, Medizinische Universität, Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>Klinische Abteilung für Rheumatologie, Medizinische Universität, Vienna</wicri:regionArea><placeName><settlement type="city">Vienne (Autriche)</settlement><region nuts="2" type="province">Vienne (Autriche)</region></placeName></affiliation></author><author><name sortKey="Sarrot Reynauld, Francoise" sort="Sarrot Reynauld, Francoise" uniqKey="Sarrot Reynauld F" first="Francoise" last="Sarrot-Reynauld">Francoise Sarrot-Reynauld</name><affiliation wicri:level="3"><nlm:affiliation>Pôle Pluridisciplinaire de Médecine, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Pôle Pluridisciplinaire de Médecine, Centre Hospitalier Universitaire de Grenoble, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation></author><author><name sortKey="Warnatz, Klaus" sort="Warnatz, Klaus" uniqKey="Warnatz K" first="Klaus" last="Warnatz">Klaus Warnatz</name><affiliation wicri:level="3"><nlm:affiliation>Division of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Freiburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Rheumatology and Clinical Immunology, University Medical Center Freiburg, Freiburg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Fribourg-en-Brisgau</region><settlement type="city">Fribourg-en-Brisgau</settlement></placeName></affiliation></author><author><name sortKey="Adoue, Daniel F P" sort="Adoue, Daniel F P" uniqKey="Adoue D" first="Daniel F P" last="Adoue">Daniel F P. Adoue</name><affiliation><nlm:affiliation>Service Médecine Interne, Centre Hospitalier Universitaire Toulouse.</nlm:affiliation><wicri:noCountry code="subField">Centre Hospitalier Universitaire Toulouse</wicri:noCountry></affiliation></author><author><name sortKey="Constans, Joel" sort="Constans, Joel" uniqKey="Constans J" first="Joël" last="Constans">Joël Constans</name><affiliation wicri:level="3"><nlm:affiliation>Service Médecine Interne et Médecine Vasculaire, Hôpital St-André, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service Médecine Interne et Médecine Vasculaire, Hôpital St-André, Centre Hospitalier Universitaire de Bordeaux, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Tony, Hans Peter" sort="Tony, Hans Peter" uniqKey="Tony H" first="Hans-Peter" last="Tony">Hans-Peter Tony</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology and Clinical Immunology, University of Würzburg Medical Center, Würzburg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Rheumatology and Clinical Immunology, University of Würzburg Medical Center, Würzburg</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Basse-Franconie</region><settlement type="city">Wurtzbourg</settlement></placeName></affiliation></author><author><name sortKey="Del Papa, Nicoletta" sort="Del Papa, Nicoletta" uniqKey="Del Papa N" first="Nicoletta" last="Del Papa">Nicoletta Del Papa</name><affiliation wicri:level="3"><nlm:affiliation>Day Hospital Reumatologia, Ospedale G. Pini, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Day Hospital Reumatologia, Ospedale G. Pini, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Fassas, Athanasios" sort="Fassas, Athanasios" uniqKey="Fassas A" first="Athanasios" last="Fassas">Athanasios Fassas</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hematology, Cell and Gene Therapy Center, George Papanicolaou Hospital, Thessaloniki, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Department of Hematology, Cell and Gene Therapy Center, George Papanicolaou Hospital, Thessaloniki</wicri:regionArea><wicri:noRegion>Thessaloniki</wicri:noRegion></affiliation></author><author><name sortKey="Himsel, Andrea" sort="Himsel, Andrea" uniqKey="Himsel A" first="Andrea" last="Himsel">Andrea Himsel</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, University Hospital Frankfurt, Frankfurt, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Rheumatology, University Hospital Frankfurt, Frankfurt</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Darmstadt</region><settlement type="city">Francfort-sur-le-Main</settlement></placeName></affiliation></author><author><name sortKey="Launay, David" sort="Launay, David" uniqKey="Launay D" first="David" last="Launay">David Launay</name><affiliation wicri:level="3"><nlm:affiliation>Service de Médecine Interne, Hôpital Claude-Huriez, Lille, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service de Médecine Interne, Hôpital Claude-Huriez, Lille</wicri:regionArea><placeName><region type="region">Hauts-de-France</region><region type="old region">Nord-Pas-de-Calais</region><settlement type="city">Lille</settlement></placeName></affiliation></author><author><name sortKey="Lo Monaco, Andrea" sort="Lo Monaco, Andrea" uniqKey="Lo Monaco A" first="Andrea" last="Lo Monaco">Andrea Lo Monaco</name><affiliation wicri:level="1"><nlm:affiliation>Section and Unit of Rheumatology, Department of Medical Sciences, University of Ferrara, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Section and Unit of Rheumatology, Department of Medical Sciences, University of Ferrara</wicri:regionArea><wicri:noRegion>University of Ferrara</wicri:noRegion></affiliation></author><author><name sortKey="Philippe, Pierre" sort="Philippe, Pierre" uniqKey="Philippe P" first="Pierre" last="Philippe">Pierre Philippe</name><affiliation wicri:level="3"><nlm:affiliation>Service de Médecine Interne, Centre Hospitalier Universitaire Estaing, Clermont-Ferrand, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service de Médecine Interne, Centre Hospitalier Universitaire Estaing, Clermont-Ferrand</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Auvergne (région administrative)</region><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author><author><name sortKey="Quere, Isabelle" sort="Quere, Isabelle" uniqKey="Quere I" first="Isabelle" last="Quéré">Isabelle Quéré</name><affiliation wicri:level="3"><nlm:affiliation>Department of Internal Medicine, Montpellier University Hospital, Montpellier, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Internal Medicine, Montpellier University Hospital, Montpellier</wicri:regionArea><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Rich, Eric" sort="Rich, Eric" uniqKey="Rich E" first="Éric" last="Rich">Éric Rich</name><affiliation wicri:level="1"><nlm:affiliation>Centre Hospitalier de l'Université de Montréal, Montréal, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre Hospitalier de l'Université de Montréal, Montréal, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Westhovens, Rene" sort="Westhovens, Rene" uniqKey="Westhovens R" first="Rene" last="Westhovens">Rene Westhovens</name><affiliation wicri:level="1"><nlm:affiliation>Skeletal Biology and Engineering Research Center, Department of Development and Regeneration KU Leuven, Rheumatology, University Hospitals, Leuven, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Skeletal Biology and Engineering Research Center, Department of Development and Regeneration KU Leuven, Rheumatology, University Hospitals, Leuven</wicri:regionArea><wicri:noRegion>Leuven</wicri:noRegion></affiliation></author><author><name sortKey="Griffiths, Bridget" sort="Griffiths, Bridget" uniqKey="Griffiths B" first="Bridget" last="Griffiths">Bridget Griffiths</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, Freeman Hospital, Newcastle upon Tyne, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Rheumatology, Freeman Hospital, Newcastle upon Tyne</wicri:regionArea><wicri:noRegion>Newcastle upon Tyne</wicri:noRegion></affiliation></author><author><name sortKey="Saccardi, Riccardo" sort="Saccardi, Riccardo" uniqKey="Saccardi R" first="Riccardo" last="Saccardi">Riccardo Saccardi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hematology, Careggi University Hospital, Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Hematology, Careggi University Hospital, Florence</wicri:regionArea><wicri:noRegion>Florence</wicri:noRegion></affiliation></author><author><name sortKey="Van Den Hoogen, Frank H" sort="Van Den Hoogen, Frank H" uniqKey="Van Den Hoogen F" first="Frank H" last="Van Den Hoogen">Frank H. Van Den Hoogen</name><affiliation wicri:level="3"><nlm:affiliation>Department of Rheumatology, Maartenskliniek, Nijmegen, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Rheumatology, Maartenskliniek, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Fibbe, Willem E" sort="Fibbe, Willem E" uniqKey="Fibbe W" first="Willem E" last="Fibbe">Willem E. Fibbe</name><affiliation wicri:level="3"><nlm:affiliation>Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden</wicri:regionArea><placeName><settlement type="city">Leyde</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Socie, Gerard" sort="Socie, Gerard" uniqKey="Socie G" first="Gérard" last="Socié">Gérard Socié</name><affiliation wicri:level="1"><nlm:affiliation>Hematology/Transplantation, AP-HP Hôpital Saint-Louis, Paris 7 University, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Hematology/Transplantation, AP-HP Hôpital Saint-Louis, Paris 7 University</wicri:regionArea><wicri:noRegion>Paris 7 University</wicri:noRegion><wicri:noRegion>Paris 7 University</wicri:noRegion></affiliation></author><author><name sortKey="Gratwohl, Alois" sort="Gratwohl, Alois" uniqKey="Gratwohl A" first="Alois" last="Gratwohl">Alois Gratwohl</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hematology, University Hospital Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Hematology, University Hospital Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Tyndall, Alan" sort="Tyndall, Alan" uniqKey="Tyndall A" first="Alan" last="Tyndall">Alan Tyndall</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Rheumatology, University Hospital Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author></analytic><series><title level="j">JAMA</title><idno type="eISSN">1538-3598</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Autografts</term><term>Cyclophosphamide (administration & dosage)</term><term>Cyclophosphamide (adverse effects)</term><term>Female</term><term>Hematopoietic Stem Cell Transplantation (adverse effects)</term><term>Humans</term><term>Immunosuppressive Agents (administration & dosage)</term><term>Immunosuppressive Agents (adverse effects)</term><term>Male</term><term>Middle Aged</term><term>Scleroderma, Diffuse (drug therapy)</term><term>Survival Analysis</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Cyclophosphamide</term><term>Immunosuppressive Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Cyclophosphamide</term><term>Immunosuppressive Agents</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Hematopoietic Stem Cell Transplantation</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Scleroderma, Diffuse</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Autografts</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Survival Analysis</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">High-dose immunosuppressive therapy and autologous hematopoietic stem cell transplantation (HSCT) have shown efficacy in systemic sclerosis in phase 1 and small phase 2 trials.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Autriche</li><li>Belgique</li><li>Canada</li><li>France</li><li>Grèce</li><li>Italie</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suisse</li></country><region><li>Alsace (région administrative)</li><li>Angleterre</li><li>Aquitaine</li><li>Auvergne (région administrative)</li><li>Auvergne-Rhône-Alpes</li><li>Bade-Wurtemberg</li><li>Bavière</li><li>District de Basse-Franconie</li><li>District de Darmstadt</li><li>District de Fribourg-en-Brisgau</li><li>District de Tübingen</li><li>Grand Est</li><li>Gueldre</li><li>Hauts-de-France</li><li>Hesse (Land)</li><li>Hollande-Méridionale</li><li>Hollande-Septentrionale</li><li>Languedoc-Roussillon</li><li>Lombardie</li><li>Nord-Pas-de-Calais</li><li>Nouvelle-Aquitaine</li><li>Occitanie (région administrative)</li><li>Provence-Alpes-Côte d'Azur</li><li>Rhône-Alpes</li><li>Vienne (Autriche)</li><li>Yorkshire-et-Humber</li><li>Île-de-France</li></region><settlement><li>Amsterdam</li><li>Bordeaux</li><li>Clermont-Ferrand</li><li>Francfort-sur-le-Main</li><li>Fribourg-en-Brisgau</li><li>Grenoble</li><li>Leeds</li><li>Leyde</li><li>Lille</li><li>Marseille</li><li>Milan</li><li>Montpellier</li><li>Nimègue</li><li>Paris</li><li>Strasbourg</li><li>Tübingen</li><li>Vienne (Autriche)</li><li>Wurtzbourg</li></settlement><orgName><li>Université de Leeds</li></orgName></list><tree><noCountry><name sortKey="Adoue, Daniel F P" sort="Adoue, Daniel F P" uniqKey="Adoue D" first="Daniel F P" last="Adoue">Daniel F P. Adoue</name><name sortKey="Deligny, Christophe" sort="Deligny, Christophe" uniqKey="Deligny C" first="Christophe" last="Deligny">Christophe Deligny</name><name sortKey="Matucci Cerinic, Marco" sort="Matucci Cerinic, Marco" uniqKey="Matucci Cerinic M" first="Marco" last="Matucci-Cerinic">Marco Matucci-Cerinic</name></noCountry><country name="Royaume-Uni"><noRegion><name sortKey="Van Laar, Jacob M" sort="Van Laar, Jacob M" uniqKey="Van Laar J" first="Jacob M" last="Van Laar">Jacob M. Van Laar</name></noRegion><name sortKey="Emery, Paul" sort="Emery, Paul" uniqKey="Emery P" first="Paul" last="Emery">Paul Emery</name><name sortKey="Griffiths, Bridget" sort="Griffiths, Bridget" uniqKey="Griffiths B" first="Bridget" last="Griffiths">Bridget Griffiths</name><name sortKey="Naraghi, Kamran" sort="Naraghi, Kamran" uniqKey="Naraghi K" first="Kamran" last="Naraghi">Kamran Naraghi</name></country><country name="France"><noRegion><name sortKey="Farge, Dominique" sort="Farge, Dominique" uniqKey="Farge D" first="Dominique" last="Farge">Dominique Farge</name></noRegion><name sortKey="Constans, Joel" sort="Constans, Joel" uniqKey="Constans J" first="Joël" last="Constans">Joël Constans</name><name sortKey="Durand, Jean Marc" sort="Durand, Jean Marc" uniqKey="Durand J" first="Jean-Marc" last="Durand">Jean-Marc Durand</name><name sortKey="Larghero, Jerome" sort="Larghero, Jerome" uniqKey="Larghero J" first="Jérôme" last="Larghero">Jérôme Larghero</name><name sortKey="Launay, David" sort="Launay, David" uniqKey="Launay D" first="David" last="Launay">David Launay</name><name sortKey="Lioure, Bruno" sort="Lioure, Bruno" uniqKey="Lioure B" first="Bruno" last="Lioure">Bruno Lioure</name><name sortKey="Marjanovic, Zora" sort="Marjanovic, Zora" uniqKey="Marjanovic Z" first="Zora" last="Marjanovic">Zora Marjanovic</name><name sortKey="Martin, Thierry" sort="Martin, Thierry" uniqKey="Martin T" first="Thierry" last="Martin">Thierry Martin</name><name sortKey="Philippe, Pierre" sort="Philippe, Pierre" uniqKey="Philippe P" first="Pierre" last="Philippe">Pierre Philippe</name><name sortKey="Quere, Isabelle" sort="Quere, Isabelle" uniqKey="Quere I" first="Isabelle" last="Quéré">Isabelle Quéré</name><name sortKey="Sarrot Reynauld, Francoise" sort="Sarrot Reynauld, Francoise" uniqKey="Sarrot Reynauld F" first="Francoise" last="Sarrot-Reynauld">Francoise Sarrot-Reynauld</name><name sortKey="Socie, Gerard" sort="Socie, Gerard" uniqKey="Socie G" first="Gérard" last="Socié">Gérard Socié</name></country><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Sont, Jacob K" sort="Sont, Jacob K" uniqKey="Sont J" first="Jacob K" last="Sont">Jacob K. Sont</name></region><name sortKey="Fibbe, Willem E" sort="Fibbe, Willem E" uniqKey="Fibbe W" first="Willem E" last="Fibbe">Willem E. Fibbe</name><name sortKey="Marijt, Erik W A" sort="Marijt, Erik W A" uniqKey="Marijt E" first="Erik W A" last="Marijt">Erik W A. Marijt</name><name sortKey="Schattenberg, Anton V" sort="Schattenberg, Anton V" uniqKey="Schattenberg A" first="Anton V" last="Schattenberg">Anton V. Schattenberg</name><name sortKey="Schuerwegh, Annemie J" sort="Schuerwegh, Annemie J" uniqKey="Schuerwegh A" first="Annemie J" last="Schuerwegh">Annemie J. Schuerwegh</name><name sortKey="Van De Loosdrecht, Arjan A" sort="Van De Loosdrecht, Arjan A" uniqKey="Van De Loosdrecht A" first="Arjan A" last="Van De Loosdrecht">Arjan A. Van De Loosdrecht</name><name sortKey="Van Den Hoogen, Frank H" sort="Van Den Hoogen, Frank H" uniqKey="Van Den Hoogen F" first="Frank H" last="Van Den Hoogen">Frank H. Van Den Hoogen</name><name sortKey="Vonk, Madelon C" sort="Vonk, Madelon C" uniqKey="Vonk M" first="Madelon C" last="Vonk">Madelon C. Vonk</name><name sortKey="Voskuyl, Alexandre E" sort="Voskuyl, Alexandre E" uniqKey="Voskuyl A" first="Alexandre E" last="Voskuyl">Alexandre E. Voskuyl</name></country><country name="Suisse"><noRegion><name sortKey="Daikeler, Thomas" sort="Daikeler, Thomas" uniqKey="Daikeler T" first="Thomas" last="Daikeler">Thomas Daikeler</name></noRegion><name sortKey="Gratwohl, Alois" sort="Gratwohl, Alois" uniqKey="Gratwohl A" first="Alois" last="Gratwohl">Alois Gratwohl</name><name sortKey="Tyndall, Alan" sort="Tyndall, Alan" uniqKey="Tyndall A" first="Alan" last="Tyndall">Alan Tyndall</name></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Kotter, Ina" sort="Kotter, Ina" uniqKey="Kotter I" first="Ina" last="Kötter">Ina Kötter</name></region><name sortKey="Himsel, Andrea" sort="Himsel, Andrea" uniqKey="Himsel A" first="Andrea" last="Himsel">Andrea Himsel</name><name sortKey="Kreuter, Alexander" sort="Kreuter, Alexander" uniqKey="Kreuter A" first="Alexander" last="Kreuter">Alexander Kreuter</name><name sortKey="Schmalzing, Marc" sort="Schmalzing, Marc" uniqKey="Schmalzing M" first="Marc" last="Schmalzing">Marc Schmalzing</name><name sortKey="Tony, Hans Peter" sort="Tony, Hans Peter" uniqKey="Tony H" first="Hans-Peter" last="Tony">Hans-Peter Tony</name><name sortKey="Warnatz, Klaus" sort="Warnatz, Klaus" uniqKey="Warnatz K" first="Klaus" last="Warnatz">Klaus Warnatz</name><name sortKey="Weiner, Stefan M" sort="Weiner, Stefan M" uniqKey="Weiner S" first="Stefan M" last="Weiner">Stefan M. Weiner</name></country><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Machold, Klaus P" sort="Machold, Klaus P" uniqKey="Machold K" first="Klaus P" last="Machold">Klaus P. Machold</name></region></country><country name="Italie"><region name="Lombardie"><name sortKey="Del Papa, Nicoletta" sort="Del Papa, Nicoletta" uniqKey="Del Papa N" first="Nicoletta" last="Del Papa">Nicoletta Del Papa</name></region><name sortKey="Lo Monaco, Andrea" sort="Lo Monaco, Andrea" uniqKey="Lo Monaco A" first="Andrea" last="Lo Monaco">Andrea Lo Monaco</name><name sortKey="Saccardi, Riccardo" sort="Saccardi, Riccardo" uniqKey="Saccardi R" first="Riccardo" last="Saccardi">Riccardo Saccardi</name></country><country name="Grèce"><noRegion><name sortKey="Fassas, Athanasios" sort="Fassas, Athanasios" uniqKey="Fassas A" first="Athanasios" last="Fassas">Athanasios Fassas</name></noRegion></country><country name="Canada"><noRegion><name sortKey="Rich, Eric" sort="Rich, Eric" uniqKey="Rich E" first="Éric" last="Rich">Éric Rich</name></noRegion></country><country name="Belgique"><noRegion><name sortKey="Westhovens, Rene" sort="Westhovens, Rene" uniqKey="Westhovens R" first="Rene" last="Westhovens">Rene Westhovens</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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